Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | WNT3A | P56704 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437162 | 0.83 | MAPT (0.50) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| SCHEMBL3652524 | 0.80 | MAPT (0.59) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| SCHEMBL1659363 | 0.79 | MAPT (0.71) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| Bromide SCHEMBL6167505 | 0.78 | MAPT (0.58) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| Hydrochloric Acid SCHEMBL3656869 | 0.78 | MAPT (0.58) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| SCHEMBL7438183 | 0.78 | CTNNB1 (0.55) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| SCHEMBL7413883 | 0.78 | MAPT (0.55) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| SCHEMBL7436967 | 0.77 | ITGB3 (0.59) | MAPTTSHRCTNNB1WNT3ACYP1A2 | |
| SCHEMBL25640423 | 0.77 | ERCC1 (0.58) | MAPTKMT2AMEN1ALDH1A1CA12 | |
| SCHEMBL11045658 | 0.76 | PDE4D (0.62) | MAPTTSHRCTNNB1WNT3ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745118-A | BRONCHODILATOR AGENTS, CARDIOTONIC AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |