Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7136748 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BROCK2NAMPTITGAV | |
| SCHEMBL6952282 | 0.80 | ITGB3 (0.66) | ITGB3ITGA2BNAMPT | |
| SCHEMBL6945837 | 0.80 | ITGB3 (0.55) | ITGB3ITGA2BROCK2NAMPTEPHX2 | |
| SCHEMBL7438405 | 0.79 | ITGB3 (0.67) | ITGB3ITGA2BROCK2ITGAV | |
| SCHEMBL6676450 | 0.77 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL6676454 | 0.77 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL8364227 | 0.72 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL6679726 | 0.72 | ITGB3 (0.51) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6679721 | 0.72 | ITGB3 (0.51) | ITGB3ITGA2BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6953549 | 0.71 | ITGB3 (0.53) | ITGB3ITGA2BROCK2NAMPTITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |