Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 11/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061424 | 0.84 | PNMT (0.58) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL383577 | 0.82 | PNMT (0.74) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL1786988 | 0.80 | PNMT (0.72) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2081772 | 0.78 | TDP2 (0.60) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL21247680 | 0.78 | TDP2 (0.60) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL30839537 | 0.78 | TDP2 (0.60) | PNMTADRA2AADRA2BADRA2C | |
| Nitric Acid SCHEMBL4718613 | 0.77 | PNMT (0.68) | PNMTADRA2AADRA2BADRA2C | |
| Nitric Acid SCHEMBL4718617 | 0.77 | PNMT (0.68) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2062101 | 0.77 | PNMT (0.62) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL7653205 | 0.73 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403578-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | SMITHKLINE BEECHAM CORPORATION | 2002-06-11 | — | — | US | disclosed |
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |