Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421857 | 0.95 | KMT2A (0.52) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2425511 | 0.94 | KMT2A (0.51) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2429271 | 0.89 | KMT2A (0.53) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2424314 | 0.89 | KMT2A (0.53) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL7443445 | 0.88 | ALDH1A1 (0.46) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2422541 | 0.88 | KMT2A (0.56) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2420859 | 0.87 | KMT2A (0.51) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2425856 | 0.87 | KMT2A (0.54) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL7439937 | 0.86 | KMT2A (0.50) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2423885 | 0.86 | LMNA (0.55) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | disclosed |