Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439282 | 0.82 | KMT2A (0.53) | HCAR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7428540 | 0.81 | HDAC3 (0.41) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7432272 | 0.81 | ALDH1A1 (0.46) | POLBALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7435457 | 0.81 | SELP (0.56) | HCAR2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7431963 | 0.79 | KDM4E (0.54) | HCAR2POLBALDH1A1MEN1KMT2A | |
| SCHEMBL7428881 | 0.79 | KDM4E (0.56) | HCAR2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7430609 | 0.77 | NPC1 (0.46) | POLBALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL7433961 | 0.76 | ABCC1 (0.47) | HCAR2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7435750 | 0.76 | KMT2A (0.47) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7438002 | 0.76 | KDM4C (0.50) | POLBALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |