Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442252 | 0.88 | SELP (0.47) | MEN1KMT2ALTB4RSELLSELP | |
| SCHEMBL7430649 | 0.88 | SELL (0.56) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7429346 | 0.86 | SELL (0.45) | NPC1ALDH1A1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL7433940 | 0.85 | LTB4R (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27520030 | 0.84 | POLB (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2HTT | |
| SCHEMBL7439374 | 0.82 | KMT2A (0.44) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7435487 | 0.82 | HDAC3 (0.49) | ALDH1A1SMN1; SMN2HTTCYP1A2CYP2C9 | |
| SCHEMBL7427426 | 0.81 | LTB4R (0.39) | CYP2C9CYP2D6MEN1KMT2ALTB4R | |
| SCHEMBL7432442 | 0.81 | L3MBTL1 (0.44) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL7432797 | 0.81 | SMN1; SMN2 (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |