Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.31 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436792 | 1.00 | RNPEP (0.40) | RNPEPSLC7A5ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL21859002 | 0.90 | RNPEP (0.36) | RNPEPSLC7A5ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL17376951 | 0.83 | RNPEP (0.40) | RNPEPSLC7A5ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL19138763 | 0.82 | SLC1A3 (0.36) | RNPEPSLC7A5SLC1A3SLC1A2MEN1 | |
| SCHEMBL1122815 | 0.80 | HSPD1 (0.34) | ALDH1A1SLC1A3SLC1A2MEN1KMT2A | |
| SCHEMBL29139332 | 0.78 | HSPD1 (0.33) | SLC1A3SLC1A2MEN1KMT2AHSPD1 | |
| SCHEMBL27585279 | 0.77 | MMP1 (0.39) | RNPEPSLC7A5ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL28637959 | 0.77 | HSPD1 (0.36) | RNPEPSLC7A5SLC1A3SLC1A2MEN1 | |
| SCHEMBL13660018 | 0.77 | RNPEP (0.41) | RNPEPSLC7A5ALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL17011642 | 0.77 | RNPEP (0.41) | RNPEPSLC7A5ALDH1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664284-A1 | Process for preparing carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-26 | — | — | EP | claimed |
| EP-0664284-A1 | Process for preparing carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-26 | — | — | EP | disclosed |