Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.53 |
| ▸ | HTR2B | P41595 | 6/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7435018 | 0.99 | HTR2C (0.52) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL467338 | 0.85 | CHRNA7 (0.52) | HTR2CHRH3 | |
| Hydrochloric Acid SCHEMBL8819343 | 0.84 | CHRNA7 (0.51) | HRH3 | |
| SCHEMBL7441143 | 0.81 | HDAC1 (0.49) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 | |
| SCHEMBL6936516 | 0.78 | CHRNA7 (0.50) | — | |
| Hydrochloric Acid SCHEMBL7436828 | 0.74 | DRD2 (0.56) | HTR2AHRH3 | |
| SCHEMBL7818940 | 0.74 | SLC6A2 (0.54) | HTR2CSLC6A2SLC6A4SLC6A3HDAC1 | |
| SCHEMBL11212875 | 0.73 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3HDAC1HDAC8 | |
| SCHEMBL29086032 | 0.71 | SLC6A2 (0.48) | HTR2CSLC6A2SLC6A4SLC6A3HDAC1 | |
| SCHEMBL11870004 | 0.71 | SLC6A2 (0.64) | HTR2CHTR2BHTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538985-A | SIDE EFFECT REDUCTION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0668275-A1 | Pyrrolidinone derivatives | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-08-23 | — | — | EP | disclosed |