Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.68 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10937862 | 0.87 | RIPK1 (0.64) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10910979 | 0.84 | RIPK1 (0.53) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1709321 | 0.81 | RIPK1 (1.00) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1709337 | 0.81 | RIPK1 (0.75) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL14776378 | 0.80 | RIPK1 (0.51) | RIPK1ALDH1A1MAPTSMN1; SMN2PPID | |
| SCHEMBL25464672 | 0.79 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL557055 | 0.79 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10990271 | 0.79 | RIPK1 (0.68) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7427096 | 0.79 | RIPK1 (0.67) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10910973 | 0.78 | RIPK1 (0.54) | RIPK1MMP8ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814622-A | COMPOUND USEFUL AS TRYPSIN LIKE SERINE PROTEASE AS THROMBIN INHIBITORS | ADIR ET COMPAGNIE (FR) | 1998-09-29 | — | — | US | disclosed |