Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.75 |
| ▸ | MMP8 | P22894 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PPIA | P62937 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20363299 | 0.90 | RIPK1 (0.67) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL21335481 | 0.88 | RIPK1 (0.58) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL1709321 | 0.86 | RIPK1 (1.00) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL15442794 | 0.83 | RIPK1 (0.54) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL20363329 | 0.83 | RIPK1 (0.62) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL1516186 | 0.83 | RIPK1 (0.71) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL18435145 | 0.82 | RIPK1 (0.69) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL432436 | 0.81 | RIPK1 (0.69) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL16644093 | 0.81 | RIPK1 (0.69) | RIPK1MMP8SMN1; SMN2OPRK1LMNA | |
| SCHEMBL20363256 | 0.81 | RIPK1 (0.59) | RIPK1MMP8SMN1; SMN2OPRK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | RIPK1 4263/4885MMP8 849/4885SMN1; SMN2 1774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.