Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22754453 | 0.81 | MAPT (0.41) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22522163 | 0.79 | SIRT5 (0.39) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10656431 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10176161 | 0.76 | MAPT (0.62) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2476070 | 0.76 | NPC1 (0.47) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18155130 | 0.76 | PPARA (0.49) | KDM4EFFAR1SIRT5MEN1KMT2A | |
| SCHEMBL2555832 | 0.74 | SIRT5 (0.51) | FFAR4KDM4EFFAR1ALDH1A1SIRT5 | |
| SCHEMBL10658982 | 0.74 | BACE1 (0.41) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20982464 | 0.74 | MAPT (0.51) | FFAR4FFAR1ALDH1A1SMN1; SMN2SIRT5 | |
| SCHEMBL5575733 | 0.74 | SIRT5 (0.44) | FFAR4KDM4EFFAR1SIRT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196428-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-03-23 | — | — | US | disclosed |