Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | SLC33A1 | O00400 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20778228 | 0.68 | AGTR1 (0.85) | AGTR1PPARGKCNH2 | |
| SCHEMBL20778212 | 0.67 | AGTR1 (0.85) | AGTR1PPARGKCNH2 | |
| SCHEMBL14245289 | 0.67 | AGTR1 (0.56) | AGTR1PPARGKCNH2SLC33A1 | |
| SCHEMBL14245122 | 0.66 | AGTR1 (0.56) | AGTR1PPARGKCNH2SLC33A1 | |
| SCHEMBL9183459 | 0.66 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL1892679 | 0.65 | AGTR1 (0.60) | AGTR1PPARGSLC33A1 | |
| SCHEMBL20778197 | 0.65 | AGTR1 (0.80) | AGTR1PPARGKCNH2 | |
| SCHEMBL12348453 | 0.64 | LTB4R2 (0.58) | LTB4R2AGTR1SLC33A1 | |
| SCHEMBL8092937 | 0.62 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL13277840 | 0.62 | AGTR1 (0.62) | AGTR1PPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628556-A1 | Imidazopyridines | MERCK PATENT GmbH (DE) | 1994-12-14 | — | — | EP | disclosed |