Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.50 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27102376 | 0.82 | BRD4 (0.62) | BRD4CREBBPBRD2 | |
| SCHEMBL17081008 | 0.78 | BRD4 (0.57) | BRD4CREBBPBRD2 | |
| SCHEMBL7342604 | 0.77 | CRBN (0.47) | — | |
| SCHEMBL5328631 | 0.75 | BRD4 (0.62) | BRD4CREBBPBRD2 | |
| SCHEMBL9768375 | 0.74 | BRD4 (0.56) | BRD4CREBBPBRD2 | |
| SCHEMBL7423824 | 0.74 | BRD4 (0.60) | BRD4CREBBPBRD2 | |
| SCHEMBL434040 | 0.73 | BRD4 (0.68) | BRD4CREBBPBRD2 | |
| SCHEMBL7413152 | 0.72 | BRD4 (0.54) | BRD4CREBBPBRD2 | |
| SCHEMBL1771061 | 0.72 | BRD4 (1.00) | BRD4CREBBPBRD2 | |
| SCHEMBL30100744 | 0.72 | BRD4 (0.66) | BRD4CREBBPBRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323479-A1 | BENZODIAZINONE-PYRIDONE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (a Delaware corporation) (US) | 1989-07-12 | — | — | EP | disclosed |
| US-4764512-A | Benzodiazinone-pyridone compounds, cardiotonic compositions including the same, and their uses | RORER PHARMACEUTICAL CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| WO-1988001508-A1 | BENZODIAZINONE-PYRIDONE COMPOUNDS, CARDIOTONIC COMPOSITIONS INCLUDING THE SAME, AND THEIR USES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1988-03-10 | — | — | WO | disclosed |