Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.62 |
| ▸ | CTSL | P07711 | 9/20 | 0.62 |
| ▸ | CTSB | P07858 | 9/20 | 0.62 |
| ▸ | CTSS | P25774 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446678 | 0.90 | CTSK (0.57) | CTSKCTSLCTSBCTSSNPC1 | |
| SCHEMBL4713651 | 0.85 | CTSK (0.79) | CTSKCTSLCTSBCTSSNPC1 | |
| SCHEMBL4717266 | 0.83 | CTSK (0.79) | CTSKCTSLCTSBCTSSNPC1 | |
| SCHEMBL4714257 | 0.76 | CTSL (1.00) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4717631 | 0.75 | CTSK (0.72) | CTSKCTSLCTSBCTSSNPC1 | |
| SCHEMBL4716426 | 0.74 | CTSK (1.00) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4760512 | 0.72 | CTSK (0.78) | CTSKCTSLCTSBCTSS | |
| SCHEMBL4715695 | 0.72 | CTSL (0.78) | CTSKCTSLCTSBCTSSNPC1 | |
| SCHEMBL2710025 | 0.71 | AR (0.72) | NPC1RAB9AKDM4EARTP53 | |
| Hydrochloric Acid SCHEMBL17541660 | 0.70 | AR (0.70) | NPC1RAB9AKDM4EARTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | disclosed |