Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424773 | 0.89 | MAPK9 (0.63) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2419998 | 0.89 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2428926 | 0.89 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL2423789 | 0.87 | MAPK9 (0.56) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL3479899 | 0.85 | MAPK9 (0.57) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL3480051 | 0.83 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL3479821 | 0.83 | MAPK9 (0.54) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL6431959 | 0.83 | MAPK9 (0.55) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL4967650 | 0.83 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ABCL2 | |
| SCHEMBL4192955 | 0.81 | MAPK9 (0.52) | MAPK9MAPK10MEN1KMT2ABCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218374-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | Applied Research Systems ARS Holding N.V. (AN) | 2002-07-03 | — | — | EP | claimed |
| WO-2001023378-A1 | PHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-05 | — | — | WO | claimed |