Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.72 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432689 | 0.87 | MEN1 (0.77) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Tofisopam SCHEMBL8086894 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Dextofisopam SCHEMBL8086913 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Tofisopam SCHEMBL29832594 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Tofisopam SCHEMBL4585183 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Dextofisopam SCHEMBL29376877 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Dextofisopam SCHEMBL236796 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| Tofisopam SCHEMBL43522 | 0.84 | KMT2A (1.00) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL14599857 | 0.82 | MEN1 (0.86) | MEN1CHRM1PDE4AKMT2APDE4D | |
| SCHEMBL7438293 | 0.81 | KMT2A (0.79) | MEN1CHRM1PDE4AKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |