Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905382 | 0.90 | KMT2A (0.54) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4045529 | 0.89 | TSHR (0.61) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL28343445 | 0.87 | GABRA1 (0.52) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL15333674 | 0.86 | KMT2A (0.50) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7448772 | 0.84 | KMT2A (0.49) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL22748797 | 0.84 | TSHR (0.52) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL969677 | 0.83 | TSHR (0.55) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9590339 | 0.82 | KMT2A (0.46) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4046233 | 0.82 | TSHR (0.53) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4880908 | 0.82 | TSHR (0.53) | KMT2AALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6333336-B1 | GAMMA-AMINOBUTYRIC ACID RECEPTORS AS ANTICONVULSANTS FORMING THE COMPOUND BY AMIDATION | MERCK SHARP & DOHME LTD. (GB) | 2001-12-25 | — | — | US | disclosed |