Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589522 | 0.93 | KMT2A (0.49) | TSHRKMT2AMEN1NOTUMALDH1A1 | |
| SCHEMBL4045529 | 0.89 | TSHR (0.61) | TSHRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3905382 | 0.86 | KMT2A (0.54) | TSHRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4181902 | 0.83 | TSHR (0.59) | TSHRKMT2AMEN1NOTUMALDH1A1 | |
| SCHEMBL7439372 | 0.83 | KMT2A (0.61) | TSHRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4880908 | 0.82 | TSHR (0.53) | TSHRKMT2AMEN1NOTUMALDH1A1 | |
| SCHEMBL4046233 | 0.82 | TSHR (0.53) | TSHRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL31540155 | 0.82 | KMT2A (0.58) | TSHRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4527744 | 0.81 | TSHR (0.61) | TSHRALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL8422423 | 0.81 | TSHR (0.61) | TSHRALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106892431-B | The manufacturing method of aerosil, heat-insulating material and aerosil | 松下知识产权经营株式会社 | 2019-12-03 | — | — | CN | claimed |
| US-10259924-B2 | Silica aerogel, heat-insulation material, and method for producing silica aerogel | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2019-04-16 | — | — | US | claimed |
| US-20170174859-A1 | SILICA AEROGEL, HEAT-INSULATION MATERIAL, AND METHOD FOR PRODUCING SILICA AEROGEL | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2017-06-22 | — | — | US | claimed |
| US-20090014920-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2009-01-15 | — | — | US | claimed |
| WO-2006001719-A1 | POLYMER FILAMENTS | MASSEY UNIVERSITY (NZ) | 2006-01-05 | — | — | WO | claimed |
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | claimed |
| JP-6298729-A | — | — | None | — | — | JP | disclosed |
| EP-4317133-B1 | CRYSTALLINE FORM OF PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2026-04-15 | — | — | EP | disclosed |
| US-20260022125-A1 | PYRROLOPYRIDAZINE VEGFR INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-01-22 | — | — | US | disclosed |
| US-12527763-B2 | Pyrrole amide compound and use thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2026-01-20 | — | — | US | disclosed |
| EP-3598536-B1 | ACTIVE MATERIAL AND BATTERY | TOYOTA MOTOR CO LTD (JP) | 2025-04-30 | — | — | EP | disclosed |
| CN-119330971-A | Compounds used as CDK7 kinase inhibitor and application thereof | 深圳艾克斯恩生物科技有限公司 | 2025-01-21 | — | — | CN | disclosed |
| US-20240376051-A1 | CRYSTALLINE FORM OF PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2024-11-14 | — | — | US | disclosed |
| US-5306443-A | Dissolving monomer with metal containing oxidizing agent in sufficient solvent to prevent polymerization; removal of solvent | NIPPON SODA CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| WO-1994004591-A1 | SOLUTION FOR COATING NON CONDUCTORS WITH CONDUCTIVE POLYMERS AND THEIR METALLIZATION PROCESS | ATOTECH DEUTSCHLAND GMBH (DE) | 1994-03-03 | — | — | WO | disclosed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4070366-A | RING ALKYLATION OF SUBSTITUTED PYRROLES, ONE STEP | CANADIAN PATENTS & DEVELOPMENT LIMITED (US) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527763-B2 | Pyrrole amide compound and use thereof | NR3C2, AVPR2, MC2R | TSHR 86/4885KMT2A 1755/4885MEN1 3769/4885 |
| US-20260022125-A1 | PYRROLOPYRIDAZINE VEGFR INHIBITORS | FLT1, KDR, FLT4 | TSHR 119/4885KMT2A 3675/4885MEN1 3386/4885 |
| US-20240376051-A1 | CRYSTALLINE FORM OF PYRROLE AMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | REN, CYP27A1, CYP4F11 | TSHR 1899/4885KMT2A 4424/4885MEN1 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.