Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425606 | 0.81 | MEN1 (0.54) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL5077522 | 0.79 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL7427961 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7435437 | 0.75 | CYP2C9 (0.57) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL4189288 | 0.74 | CASR (0.59) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL21307626 | 0.73 | HDAC1 (0.77) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL7434266 | 0.72 | MME (0.57) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL3731687 | 0.72 | CASR (0.54) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL560143 | 0.71 | L3MBTL1 (0.57) | ALDH1A1MEN1KMT2ALMNAALOX12 | |
| SCHEMBL14426490 | 0.69 | HDAC1 (0.70) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |