Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665299 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2PIM1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29507440 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2PIM1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15665079 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2PIM1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7399539 | 0.76 | PORCN (0.49) | SMN1; SMN2PIM1BRS3 | |
| SCHEMBL29290691 | 0.73 | PIM1 (0.40) | PIM1KMT2AKDM4EALDH1A1GPR119 | |
| SCHEMBL8104378 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AALDH1A1HSD17B10BRS3 | |
| SCHEMBL13603832 | 0.72 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AALDH1A1HSD17B10BRS3 | |
| SCHEMBL31173895 | 0.71 | PIM1 (0.56) | SMN1; SMN2PIM1ALDH1A1GPR119CHRNB2 | |
| SCHEMBL28570406 | 0.71 | PIM1 (0.56) | SMN1; SMN2PIM1ALDH1A1GPR119CHRNB2 | |
| SCHEMBL15664903 | 0.71 | PIM1 (0.56) | SMN1; SMN2PIM1ALDH1A1GPR119CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080920-A1 | ARYLACETAMIDO-KETOBENZOXAZOLE AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | WO | claimed |
| US-20020156063-A1 | Arylacetamido-ketobenzoxazole as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156063-A1 | Arylacetamido-ketobenzoxazole as cysteine protease inhibitors | SERPINB1, SPINT2, PRSS1 | SMN1; SMN2 4367/4885CPT2 3151/4885CPT1A 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.