Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 11/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.61 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.61 |
| ▸ | HTR3B | O95264 | 1/20 | 0.61 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.61 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.61 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430281 | 1.00 | HTR3A (0.68) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7346706 | 0.91 | HTR3A (0.67) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7339588 | 0.91 | HTR3A (0.67) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7364679 | 0.89 | HTR3A (0.83) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7497547 | 0.89 | HTR3A (0.83) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7433490 | 0.89 | HTR3A (0.66) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7426780 | 0.89 | HTR3A (0.66) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7341141 | 0.89 | HTR3A (0.67) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7343233 | 0.89 | HTR3A (0.70) | HTR3AALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7337321 | 0.89 | HTR3A (0.67) | HTR3AALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469449-B1 | Diazabicyclononyl derivatives as 5-HT3 receptor antagonists | NISSHIN FLOUR MILLING CO (JP) | 1997-10-01 | — | — | EP | disclosed |