Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779254 | 0.85 | ALDH1A1 (0.38) | ALDH1A1ELANETDP1PRKCANAAA | |
| SCHEMBL5780612 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ELANETDP1 | |
| SCHEMBL65267 | 0.71 | ELANE (0.40) | ALDH1A1ELANEPRKCA | |
| SCHEMBL7989586 | 0.70 | ELANE (0.34) | ALDH1A1ELANETDP1PRKCA | |
| SCHEMBL9669061 | 0.70 | — | — | |
| SCHEMBL8921549 | 0.70 | TSHR (0.42) | ALDH1A1ELANEPRKCANAAA | |
| Pivalate SCHEMBL27747014 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TDP1NAAA | |
| SCHEMBL7338739 | 0.70 | NAAA (0.40) | ALDH1A1ELANEPRKCANAAA | |
| SCHEMBL4631690 | 0.70 | ALDH1A1 (0.64) | ALDH1A1ELANEPRKCANAAA | |
| SCHEMBL4316110 | 0.69 | ALDH1A1 (0.53) | ALDH1A1ELANETDP1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1997048395-A1 | IONTOPHORETIC DELIVERY OF INTEGRIN INHIBITORS | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-12-24 | — | — | WO | claimed |
| US-4652560-A | ANTIBIOTICS, BACTERICIDES | BEECHAM GROUP P.L.C. (GB) | 1987-03-24 | — | — | US | disclosed |