Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.55 |
| ▸ | ACE | P12821 | 3/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | FURIN | P09958 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439860 | 1.00 | F10 (0.55) | F10ACEMMECPA1ACE2 | |
| SCHEMBL10816310 | 0.90 | GPR132 (0.66) | ACEMMECPA1ACE2GPR132 | |
| Iodide SCHEMBL7430202 | 0.88 | F2 (0.53) | F10ACEMMECPA1ACE2 | |
| SCHEMBL7434379 | 0.83 | GPR132 (0.56) | ACEMMECPA1ACE2GPR132 | |
| SCHEMBL7434372 | 0.83 | GPR132 (0.56) | ACEMMECPA1ACE2GPR132 | |
| SCHEMBL1123234 | 0.81 | GPR132 (0.71) | GPR132ITGB3ITGA2BPTPN1 | |
| SCHEMBL11037416 | 0.80 | GPR132 (0.66) | ACEGPR132ITGB3ITGA2BCA2 | |
| SCHEMBL5921805 | 0.79 | GPR132 (0.62) | ACEGPR132CA2CA1PTPN1 | |
| SCHEMBL5921800 | 0.79 | GPR132 (0.62) | ACEGPR132CA2CA1PTPN1 | |
| SCHEMBL1123282 | 0.79 | PTPN1 (0.58) | ACEMMECPA1ACE2GPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | claimed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | claimed |