Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 12/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 3/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440172 | 1.00 | F11 (0.60) | F11PRSS1PRSS2PRSS3KLKB1 | |
| Hydrochloric Acid SCHEMBL7435430 | 0.92 | F11 (0.58) | F11PRSS1PRSS2PRSS3KLKB1 | |
| Hydrochloric Acid SCHEMBL7435422 | 0.92 | F11 (0.58) | F11PRSS1PRSS2PRSS3KLKB1 | |
| SCHEMBL7540226 | 0.90 | PLG (0.61) | F11PRSS1PRSS2PRSS3KLKB1 | |
| SCHEMBL7540234 | 0.90 | PLG (0.61) | F11PRSS1PRSS2PRSS3KLKB1 | |
| Hydrochloric Acid SCHEMBL7275801 | 0.89 | PLG (0.60) | F11PRSS1PRSS2PRSS3KLKB1 | |
| Hydrochloric Acid SCHEMBL7545755 | 0.89 | PLG (0.60) | F11PRSS1PRSS2PRSS3KLKB1 | |
| Hydrochloric Acid SCHEMBL7448099 | 0.88 | F11 (0.55) | F11PRSS1PRSS2PRSS3KLKB1 | |
| Hydrochloric Acid SCHEMBL7448102 | 0.88 | F11 (0.55) | F11PRSS1PRSS2PRSS3KLKB1 | |
| SCHEMBL7432240 | 0.86 | F11 (0.53) | F11PRSS1PRSS2PRSS3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | disclosed |