Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440242 | 1.00 | MME (0.53) | MMEACECPA1ACE2MMP9 | |
| Hydrochloric Acid SCHEMBL7445392 | 0.99 | MME (0.53) | MMEACECPA1ACE2MMP9 | |
| Hydrochloric Acid SCHEMBL7894690 | 0.99 | MME (0.53) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7408594 | 0.91 | REN (0.56) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833134 | 0.91 | MME (0.50) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833138 | 0.91 | MME (0.50) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833547 | 0.89 | GPR132 (0.50) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL5833543 | 0.89 | GPR132 (0.50) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7450328 | 0.88 | MME (0.52) | MMEACECPA1ACE2MMP9 | |
| SCHEMBL7450317 | 0.88 | MME (0.52) | MMEACECPA1ACE2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323243-B1 | AROMATIC ETHER WITH AMINE OR AMIDE GROUPS | WARNER-LAMBERT COMPANY | 2001-11-27 | — | — | US | claimed |
| US-6180677-B1 | ANTIEPILEPSY AGENT | WARNER-LAMBERT COMPANY | 2001-01-30 | — | — | US | claimed |
| WO-2000006535-A1 | TYROSINE-DERIVED COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | claimed |
| US-6323243-B1 | AROMATIC ETHER WITH AMINE OR AMIDE GROUPS | WARNER-LAMBERT COMPANY | 2001-11-27 | — | — | US | disclosed |
| US-6180677-B1 | ANTIEPILEPSY AGENT | WARNER-LAMBERT COMPANY | 2001-01-30 | — | — | US | disclosed |
| WO-2000006535-A1 | TYROSINE-DERIVED COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |