Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395613 | 0.89 | DGAT1 (0.40) | DGAT1ALDH1A1CA2APLNRTDP1 | |
| SCHEMBL4288100 | 0.81 | DGAT1 (0.50) | DGAT1ALDH1A1TET2CA12CA14 | |
| SCHEMBL7551301 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TET2CA2GAA | |
| SCHEMBL1798280 | 0.76 | ALDH1A1 (0.68) | DGAT1ALDH1A1TET2CA12CA14 | |
| SCHEMBL1820007 | 0.76 | ALDH1A1 (0.68) | DGAT1ALDH1A1TET2CA12CA14 | |
| SCHEMBL4317965 | 0.75 | ALDH1A1 (0.42) | ALDH1A1GAA | |
| SCHEMBL78520 | 0.74 | DGAT1 (0.46) | DGAT1ALDH1A1CA12CA14CA2 | |
| SCHEMBL4147427 | 0.73 | ALDH1A1 (0.44) | DGAT1ALDH1A1TET2CA12CA14 | |
| SCHEMBL1088879 | 0.73 | DGAT1 (0.40) | DGAT1ALDH1A1CA2TDP1CA1 | |
| SCHEMBL3844213 | 0.73 | DGAT1 (0.40) | DGAT1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651756-A1 | TRICYCLIC DEFEM SULPHONES AS ELASTASE INHIBITORS | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-05-10 | — | — | EP | claimed |
| WO-1994028003-A1 | TRICYCLIC DEFEM SULPHONES AS ELASTASE INHIBITORS | PHARMACIA S.P.A. (IT) | 1994-12-08 | — | — | WO | claimed |