Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24819015 | 0.94 | TP53 (0.31) | KDM4E | |
| SCHEMBL919269 | 0.70 | MAPK1 (0.34) | KDM4E | |
| SCHEMBL23782146 | 0.67 | MAPK1 (0.38) | — | |
| SCHEMBL23794156 | 0.67 | MAPK1 (0.38) | — | |
| SCHEMBL3862997 | 0.67 | MAPK1 (0.39) | KDM4E | |
| SCHEMBL14641066 | 0.61 | ICAM1 (0.32) | — | |
| SCHEMBL6898725 | 0.61 | TP53 (0.32) | KDM4E | |
| SCHEMBL17007220 | 0.60 | — | — | |
| SCHEMBL14863546 | 0.59 | HSD11B1 (0.33) | KDM4E | |
| SCHEMBL16054182 | 0.59 | MGLL (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538332-B1 | POLYCYCLIC GUANINE DERIVATIVES | SCHERING CORP (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5393755-A | Hypotensive agents, enzyme inhibitors | SCHERING CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| WO-1991019717-A1 | POLYCYCLIC GUANINE DERIVATIVES | SCHERING CORPORATION (US) | 1991-12-26 | — | — | WO | disclosed |