Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 14/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513038 | 0.81 | ACHE (0.60) | HRH4HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28522595 | 0.80 | ACHE (0.56) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL2455891 | 0.79 | HRH4 (0.48) | HRH4HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21359259 | 0.79 | ACHE (0.51) | HRH4HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31614616 | 0.78 | ACHE (0.55) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL10580487 | 0.78 | ACHE (0.55) | NPC1RAB9ASMN1; SMN2LMNAACHE | |
| SCHEMBL7046687 | 0.78 | NPC1 (0.48) | HRH4HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21359173 | 0.77 | ACHE (0.50) | HRH4HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20528136 | 0.77 | NPC1 (0.47) | HRH4HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1287156 | 0.76 | NPC1 (0.49) | HRH4HRH3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |