Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863317 | 0.81 | PTGDR2 (0.47) | SLC6A3SLC6A4 | |
| SCHEMBL3467997 | 0.77 | CHRM1 (0.43) | HTR3ASLC6A3SLC6A4SLC6A2CHRM2 | |
| SCHEMBL3467999 | 0.77 | CHRM1 (0.43) | HTR3ASLC6A3SLC6A4SLC6A2CHRM2 | |
| SCHEMBL7968131 | 0.76 | MEN1 (0.39) | SLC6A3SLC6A4CHRM2CHRM1 | |
| SCHEMBL7968135 | 0.76 | MEN1 (0.39) | SLC6A3SLC6A4CHRM2CHRM1 | |
| SCHEMBL6506784 | 0.73 | HTR3A (0.62) | HTR3ASLC6A4CHRM1CHRM3 | |
| SCHEMBL6506786 | 0.73 | HTR3A (0.62) | HTR3ASLC6A4CHRM1CHRM3 | |
| SCHEMBL12965677 | 0.72 | SMN1; SMN2 (0.52) | — | |
| SCHEMBL16836609 | 0.72 | SLC6A3 (0.45) | SLC6A3SLC6A4 | |
| SCHEMBL4384293 | 0.72 | SLC6A3 (0.43) | HTR3ASLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024030-A1 | PYRROLIDINE DERIVATIVES | GUILFORD PHARMACEUTICALS INC. (US) | 1997-07-10 | — | — | WO | disclosed |