Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451071 | 0.94 | NQO1 (0.34) | NQO1CYP2C9 | |
| SCHEMBL7437094 | 0.93 | NQO1 (0.33) | NQO1NPY5RCYP2C9 | |
| SCHEMBL7443597 | 0.92 | MAPT (0.34) | NQO1NPY5RCYP2C9 | |
| SCHEMBL7440406 | 0.92 | NQO1 (0.33) | NQO1CYP2C9 | |
| SCHEMBL7443735 | 0.91 | TP53 (0.35) | NQO1CYP2C9 | |
| SCHEMBL7440164 | 0.91 | CNR1 (0.34) | NQO1 | |
| SCHEMBL9281720 | 0.91 | CNR1 (0.34) | NQO1 | |
| SCHEMBL7443023 | 0.90 | NQO1 (0.37) | NQO1CYP2C9 | |
| SCHEMBL7439540 | 0.86 | NQO1 (0.34) | NQO1NPY5R | |
| SCHEMBL7443688 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |
| EP-1203770-A1 | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hyperplasia and other diseases | PHARMACIA & UPJOHN COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-1994011361-A1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | THE UPJOHN COMPANY (US) | 1994-05-26 | — | — | WO | disclosed |