Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359041 | 0.84 | MEN1 (0.61) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL7279555 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL11360125 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL7438879 | 0.84 | ALDH1A1 (0.71) | ALDH1A1GAAKMT2AMEN1KDM4E | |
| SCHEMBL7435574 | 0.80 | POLB (0.59) | MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL7439654 | 0.78 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL31520481 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL31520492 | 0.77 | KMT2A (0.63) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL31520487 | 0.77 | MEN1 (0.68) | ALDH1A1GAAKMT2AMEN1KDM4E | |
| SCHEMBL31520486 | 0.77 | ALDH1A1 (0.67) | ALDH1A1GAAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |