Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439654 | 0.86 | ALDH1A1 (0.71) | ALDH1A1KDM4EKMT2AMEN1GAA | |
| SCHEMBL7440438 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7282346 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7434650 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2ALMNACYP1A2 | |
| SCHEMBL7437444 | 0.77 | KMT2A (0.64) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7434820 | 0.75 | ALDH1A1 (0.68) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL26498772 | 0.74 | CACNA1H (0.64) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL7426498 | 0.74 | ME2 (0.58) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL5336327 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1LMNAGAA | |
| SCHEMBL7431609 | 0.72 | NPC1 (0.51) | ALDH1A1KDM4EKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |