Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.69 |
| ▸ | CTSL | P07711 | 8/20 | 0.52 |
| ▸ | CTSB | P07858 | 8/20 | 0.52 |
| ▸ | CTSH | P09668 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757825 | 0.93 | CTSK (0.61) | CTSKCTSLCTSBCTSH | |
| SCHEMBL30314267 | 0.90 | CTSK (0.57) | CTSKCTSLCTSB | |
| SCHEMBL5703708 | 0.90 | CTSK (0.57) | CTSKCTSLCTSB | |
| SCHEMBL17175565 | 0.86 | CTSK (0.55) | CTSKCTSLCTSBCTSH | |
| SCHEMBL19057194 | 0.86 | CTSK (0.55) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7380626 | 0.85 | CTSK (0.59) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7280943 | 0.84 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL5675391 | 0.84 | CTSK (0.65) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7040369 | 0.84 | CTSK (0.57) | CTSKCTSLCTSBCTSH | |
| SCHEMBL2479459 | 0.83 | CTSK (0.51) | CTSKCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900081-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-0900081-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997036591-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| EP-0703905-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO. INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0577775-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1995-01-11 | — | — | EP | disclosed |
| EP-0577775-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1994-01-12 | — | — | EP | disclosed |
| WO-1992017196-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-10-15 | — | — | WO | disclosed |