Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSH | P09668 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040369 | 1.00 | CTSK (0.57) | CTSKNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2479459 | 0.89 | CTSK (0.51) | CTSKNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL5703708 | 0.87 | CTSK (0.57) | CTSKHPGDCTSLCTSBEPHX1 | |
| SCHEMBL30314267 | 0.87 | CTSK (0.57) | CTSKHPGDCTSLCTSBEPHX1 | |
| SCHEMBL26036961 | 0.85 | CTSK (0.45) | CTSKCTSLCTSB | |
| SCHEMBL15757825 | 0.84 | CTSK (0.61) | CTSKCTSLCTSBCTSHEPHX1 | |
| SCHEMBL7440472 | 0.84 | CTSK (0.69) | CTSKCTSLCTSBCTSH | |
| SCHEMBL7380626 | 0.82 | CTSK (0.59) | CTSKCTSLCTSBCTSH | |
| SCHEMBL8491330 | 0.80 | CTSK (0.47) | CTSKNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL9540332 | 0.80 | CTSK (0.47) | CTSKNPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107761-A2 | 4-QUINOLINEMETHANOL DERIVATIVES AS PURINE RECEPTOR ANTAGONISTS (II) | VERNALIS RESEARCH LIMITED (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000013682-A2 | 4-QUINOLINEMETHANOL DERIVATIVES AS PURINE RECEPTOR ANTAGONISTS.(II) | VERNALIS RESEARCH LIMITED (GB) | 2000-03-16 | — | — | WO | disclosed |
| WO-1993012076-A1 | REAGENTS FOR AUTOMATED SYNTHESIS OF PEPTIDE ANALOGS | CORVAS INTERNATIONAL INC. (US) | 1993-06-24 | — | — | WO | disclosed |
| EP-0376012-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0309766-A2 | N-acylamino acid derivatives and their use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-05 | — | — | EP | disclosed |