SCHEMBL744054

SCHEMBL744054

COc1cc(-c2ccccc2-c2ccccc2)ccn1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.50
DYRK1A Q13627 1/20 0.48
ACVR2A P27037 5/20 0.47
TGFBR2 P37173 5/20 0.47
CYP19A1 P11511 1/20 0.46
LOX P28300 1/20 0.43
LOXL2 Q9Y4K0 1/20 0.43
TGFBR1 P36897 2/20 0.43
CNR1 P21554 1/20 0.43
LRRK2 Q5S007 2/20 0.43
WNT3A P56704 1/20 0.42
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
ATR Q13535 1/20 0.41
PDE10A Q9Y233 1/20 0.41
FAAH O00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16404625 0.87 CNR1 (0.49) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL17376184 0.84 ACVR2A (0.49) IDO1DYRK1AACVR2ATGFBR2TGFBR1
SCHEMBL22283951 0.83 IDO1 (0.48) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL30042559 0.83 IDO1 (0.48) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL30626327 0.80 LOX (0.55) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL16116782 0.80 LOX (0.55) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL17504880 0.79 IDO1 (0.48) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL1264943 0.78 DYRK1A (0.45) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL29890032 0.78 GSK3B (0.47) IDO1DYRK1AACVR2ATGFBR2CYP19A1
SCHEMBL21380856 0.77 GRM5 (0.47) IDO1DYRK1AACVR2ATGFBR2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107325089-B 2-azatriphenylene materials for organic light emitting diodes 通用显示公司 2021-07-13 CN disclosed
EP-2520571-B1 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORP (US) 2016-08-17 EP disclosed
EP-2520571-B1 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORP (US) 2016-08-17 EP disclosed
US-9005771-B2 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-04-14 US disclosed
US-9005771-B2 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-04-14 US disclosed
US-9005771-B2 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-04-14 US disclosed
EP-2429997-B1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2014-01-15 EP disclosed
EP-2429997-B1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2014-01-15 EP disclosed
EP-2520571-A1 2-azatriphenylene materials for organic light emitting diodes Universal Display Corporation (US) 2012-11-07 EP disclosed
CN-102482222-A 2-azatriphenylene materials for organic light emitting diodes UNIVERSAL DISPLAY CORP 2012-05-30 CN disclosed
EP-2429997-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES Universal Display Corporation (US) 2012-03-21 EP disclosed
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 US disclosed
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 US disclosed
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 US disclosed
WO-2010132524-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 WO disclosed
WO-2010132524-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2010-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100289406-A1 2-AZATRIPHENYLENE MATERIALS FOR ORGANIC LIGHT EMITTING DIODES DDT, NR2E3, ALKBH2 IDO1 180/4885DYRK1A 2899/4885ACVR2A 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.