Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24989594 | 0.97 | NAAA (0.42) | MCL1EPHX2TEAD3TSHRHTT | |
| SCHEMBL7428202 | 0.91 | MCL1 (0.45) | MCL1EPHX2TSHRHTTSMN1; SMN2 | |
| SCHEMBL956809 | 0.81 | NPC1 (0.48) | MCL1TSHRSMN1; SMN2L3MBTL1MME | |
| SCHEMBL1988984 | 0.80 | EPHX2 (0.48) | EPHX2TEAD3TSHRHTTSMN1; SMN2 | |
| SCHEMBL15869131 | 0.80 | TSHR (0.45) | EPHX2TEAD3TSHRHTTSMN1; SMN2 | |
| SCHEMBL24872943 | 0.80 | SMN1; SMN2 (0.47) | EPHX2TEAD3TSHRHTTSMN1; SMN2 | |
| SCHEMBL25269510 | 0.79 | EPHX2 (0.57) | EPHX2TEAD3TSHRHTTSMN1; SMN2 | |
| SCHEMBL19032713 | 0.79 | EPHX2 (0.57) | EPHX2TEAD3TSHRHTTSMN1; SMN2 | |
| SCHEMBL10081325 | 0.79 | EPHX2 (0.57) | EPHX2TEAD3TSHRHTTSMN1; SMN2 | |
| SCHEMBL291194 | 0.79 | SMN1; SMN2 (0.57) | EPHX2TEAD3TSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874760-A | CALCIUM ANTAGONISTS | TOA EIYO, LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| EP-0277701-A1 | Thiazolopyridine derivative, their production and cardiovascular treating agents containing them | TOA EIYO LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |