SCHEMBL7428202

SCHEMBL7428202

N#CCC(=O)CCOCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.45
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.42
HTT P42858 1/20 0.42
MME P08473 1/20 0.40
ALDH1A1 P00352 4/20 0.40
NAAA Q02083 1/20 0.40
LMNA P02545 1/20 0.40
CTSS P25774 1/20 0.39
FOLH1 Q04609 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
EPHX2 P34913 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7440542 0.91 MCL1 (0.43) MCL1TSHRSMN1; SMN2HTTMME
SCHEMBL24989594 0.88 NAAA (0.42) MCL1TSHRSMN1; SMN2HTTNAAA
SCHEMBL7708032 0.84 TSHR (0.56) TSHRSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL956809 0.83 NPC1 (0.48) MCL1TSHRSMN1; SMN2MMEALDH1A1
SCHEMBL14722398 0.82 F2RL1 (0.45) SMN1; SMN2HTTALDH1A1TDP1L3MBTL1
SCHEMBL28739368 0.80 ALDH1A1 (0.52) TSHRSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL15862001 0.80 NPC1 (0.50) TSHRSMN1; SMN2HTTALDH1A1NAAA
SCHEMBL11584476 0.79 TDP1 (0.49) MCL1TSHRSMN1; SMN2HTTALDH1A1
SCHEMBL12655265 0.78 TSHR (0.48) TSHRSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL8316692 0.78 SMN1; SMN2 (0.49) TSHRSMN1; SMN2HTTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115651122-A Pour point depressant, and preparation method and application thereof 德仕能源科技集团股份有限公司 2023-01-31 CN claimed
CN-115651122-A Pour point depressant, and preparation method and application thereof 德仕能源科技集团股份有限公司 2023-01-31 CN disclosed
WO-2022110052-A1 NITROGEN-CONTAINING HETEROCYCLIC 5-HT3 RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 科岭源生物科技(深圳)有限公司 2022-06-02 WO disclosed
WO-2022110052-A1 NITROGEN-CONTAINING HETEROCYCLIC 5-HT3 RECEPTOR MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 科岭源生物科技(深圳)有限公司 2022-06-02 WO disclosed
CN-112390799-B Nitrogen-containing heterocyclic 5-HT3 receptor regulator and preparation method and application thereof 科岭源生物科技(深圳)有限公司 2022-04-29 CN disclosed
CN-112390799-A Nitrogen-containing heterocyclic 5-HT3 receptor regulator and preparation method and application thereof 成都科岭源医药技术有限公司 2021-02-23 CN disclosed
US-4874760-A CALCIUM ANTAGONISTS TOA EIYO, LTD. (JP) 1989-10-17 US disclosed
EP-0277701-A1 Thiazolopyridine derivative, their production and cardiovascular treating agents containing them TOA EIYO LTD. (JP) 1988-08-10 EP disclosed