Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.72 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.50 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475597 | 0.92 | NAPRT (0.62) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL3383611 | 0.90 | NAPRT (0.66) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL31473447 | 0.90 | NAPRT (0.66) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL29457431 | 0.88 | NPC1 (0.62) | NAPRTDGAT1SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL4467915 | 0.88 | NPC1 (0.62) | NAPRTDGAT1SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL5305773 | 0.88 | NAPRT (0.58) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL17676098 | 0.88 | RAB9A (0.64) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| Hydrochloric Acid SCHEMBL7478607 | 0.87 | NAPRT (0.61) | NAPRTRAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| Hydrochloric Acid SCHEMBL7478603 | 0.87 | NAPRT (0.61) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 | |
| SCHEMBL17801 | 0.86 | NAPRT (0.72) | NAPRTDGAT1RAB9ASMN1; SMN2KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863755-A4 | ANTITHROMBOTIC DIAMINES | LILLY CO ELI (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0863755-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997025033-A1 | ANTITHROMBOTIC DIAMINES | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |