Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.62 |
| ▸ | CTSS | P25774 | 17/20 | 0.62 |
| ▸ | CTSL | P07711 | 15/20 | 0.62 |
| ▸ | CTSB | P07858 | 11/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4711952 | 0.87 | CTSK (0.67) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712579 | 0.82 | CTSK (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL7440880 | 0.81 | CTSK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4714895 | 0.78 | CTSK (0.68) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4713554 | 0.77 | CTSK (1.00) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4716242 | 0.77 | CTSK (0.72) | CTSKCTSSCTSLCTSB | |
| SCHEMBL6247225 | 0.77 | CTSK (0.65) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4711959 | 0.77 | CTSK (0.79) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4718649 | 0.77 | CTSK (0.71) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4712421 | 0.76 | CTSK (0.74) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049288-A9 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2001-10-25 | — | — | WO | disclosed |