Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CHRNA10 | Q9GZZ6 | 5/20 | 0.54 |
| ▸ | CHRNA9 | Q9UGM1 | 5/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696074 | 0.96 | LTA4H (0.66) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL2242613 | 0.95 | LTA4H (0.64) | LTA4HRELACHRNA7TP53CHRNA10 | |
| SCHEMBL1618632 | 0.89 | RELA (0.72) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL5741015 | 0.89 | RELA (0.72) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL2089335 | 0.86 | NR5A1 (0.63) | LTA4HMAPTKDM4EALDH1A1TP53 | |
| SCHEMBL2622559 | 0.85 | CHRNA7 (0.63) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL5739190 | 0.84 | CHRNA7 (0.68) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL5739187 | 0.84 | CHRNA7 (0.68) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL5740096 | 0.84 | CHRNA7 (0.68) | LTA4HRELACHRNA7MAPTKDM4E | |
| SCHEMBL7538209 | 0.84 | CHRNA7 (0.68) | LTA4HRELACHRNA7MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128337-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-07 | — | — | US | claimed |