Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19852352 | 0.87 | SIGMAR1 (0.40) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL19289692 | 0.86 | SIGMAR1 (0.43) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL8426777 | 0.85 | TRPM8 (0.42) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL15075010 | 0.81 | SIGMAR1 (0.45) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL8970282 | 0.80 | SIGMAR1 (0.40) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL11256078 | 0.80 | SIGMAR1 (0.44) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL7439505 | 0.79 | SIGMAR1 (0.43) | SIGMAR1DRD2HTR2AADRA1DADRA1A | |
| SCHEMBL6051120 | 0.79 | SIGMAR1 (0.43) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL1797048 | 0.79 | SIGMAR1 (0.43) | SIGMAR1DRD2HTR2ACYP2D6TSHR | |
| SCHEMBL547117 | 0.77 | SIGMAR1 (0.42) | SIGMAR1DRD2HTR2ACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507637-A2 | Use of benzobicyclic carboxamides for the manufacture of a medicament for use as analgesic | Erbamont Inc. (US) | 1992-10-07 | — | — | EP | claimed |
| EP-0493041-A2 | Use of benzobicyclic carboxamides for the treatment of anxiety and migraine | ERBAMONT, INC. (US) | 1992-07-01 | — | — | EP | claimed |
| US-5122528-A | N-(1-azabicyclo(2.2.2)octyl) or N-((8-phenmethyl)-8-azabicyclo (3.2.1)octyl) benzofuryl, chromenyl or 1-benzoxepinyl carboxamides | ERBAMONT, INC. (US) | 1992-06-16 | — | — | US | claimed |
| EP-0507637-A3 | USE OF BENZOBICYCLIC CARBOXAMIDES FOR THE MANUFACTURE OF A MEDICAMENT FOR USE AS ANALGESIC | Erbamont Inc. (US) | 1992-11-19 | — | — | EP | disclosed |
| EP-0507637-A2 | Use of benzobicyclic carboxamides for the manufacture of a medicament for use as analgesic | Erbamont Inc. (US) | 1992-10-07 | — | — | EP | disclosed |
| EP-0507637-A2 | Use of benzobicyclic carboxamides for the manufacture of a medicament for use as analgesic | Erbamont Inc. (US) | 1992-10-07 | — | — | EP | disclosed |
| EP-0493041-A2 | Use of benzobicyclic carboxamides for the treatment of anxiety and migraine | ERBAMONT, INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| EP-0493041-A2 | Use of benzobicyclic carboxamides for the treatment of anxiety and migraine | ERBAMONT, INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| US-5122528-A | N-(1-azabicyclo(2.2.2)octyl) or N-((8-phenmethyl)-8-azabicyclo (3.2.1)octyl) benzofuryl, chromenyl or 1-benzoxepinyl carboxamides | ERBAMONT, INC. (US) | 1992-06-16 | — | — | US | disclosed |
| US-5114947-A | Benzofuran-7-carboxamides as anxiolytic agents | ERBAMONT INC. (US) | 1992-05-19 | — | — | US | disclosed |