Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440530 | 0.70 | MMP8 (0.39) | MMP8ALDH1A1MAPTKMT2A | |
| SCHEMBL8532813 | 0.67 | MMP8 (0.42) | MMP8 | |
| SCHEMBL7046980 | 0.65 | HSD17B10 (0.39) | — | |
| SCHEMBL31674162 | 0.64 | MMP8 (0.38) | MMP8ALDH1A1KMT2A | |
| SCHEMBL17617148 | 0.64 | MMP8 (0.56) | MMP8ALDH1A1MAPTKMT2A | |
| SCHEMBL17617202 | 0.64 | MMP8 (0.56) | MMP8ALDH1A1MAPTKMT2A | |
| SCHEMBL4426319 | 0.63 | MMP8 (0.76) | MMP8ALDH1A1MAPTKMT2A | |
| SCHEMBL7857447 | 0.63 | MMP8 (0.59) | MMP8ALDH1A1MAPTKMT2A | |
| SCHEMBL10894245 | 0.63 | TSHR (0.39) | ALDH1A1 | |
| SCHEMBL8797960 | 0.63 | MMP8 (0.38) | MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013792-A | INTERSTITIAL COLLAGENASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIOSTEOPOROSIS AGENTS | SYNTEX (U.S.A.), INC. (US) | 2000-01-11 | — | — | US | disclosed |
| EP-0712403-B1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1997-09-10 | — | — | EP | disclosed |
| EP-0712403-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004735-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-02-16 | — | — | WO | disclosed |