Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.56 |
| ▸ | PLG | P00747 | 4/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | F11 | P03951 | 12/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441164 | 1.00 | PRSS1 (0.56) | PRSS1PRSS2PRSS3KLKB1PLG | |
| SCHEMBL7440589 | 0.89 | PRSS1 (0.63) | PRSS1PRSS2PRSS3KLKB1PLG | |
| SCHEMBL7440593 | 0.89 | PRSS1 (0.63) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7434363 | 0.88 | PRSS1 (0.62) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7434371 | 0.88 | PRSS1 (0.62) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7445118 | 0.82 | PRSS1 (0.52) | PRSS1PRSS2PRSS3KLKB1PLG | |
| SCHEMBL7440177 | 0.81 | F11 (0.60) | PRSS1PRSS2PRSS3KLKB1PLG | |
| SCHEMBL7440172 | 0.81 | F11 (0.60) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7435422 | 0.80 | F11 (0.58) | PRSS1PRSS2PRSS3KLKB1PLG | |
| Hydrochloric Acid SCHEMBL7435430 | 0.80 | F11 (0.58) | PRSS1PRSS2PRSS3KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | claimed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | claimed |