Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912355 | 0.92 | KLK7 (0.61) | KLK7TLR2TLR1ALDH1A1TSHR | |
| SCHEMBL29401167 | 0.92 | KLK7 (0.61) | KLK7TLR2TLR1ALDH1A1TSHR | |
| SCHEMBL3911500 | 0.81 | KLK7 (0.57) | KLK7TLR2TLR1ALDH1A1 | |
| SCHEMBL10522656 | 0.79 | KLK7 (0.47) | KLK7TLR2TLR1 | |
| SCHEMBL29398857 | 0.78 | KLK7 (0.53) | KLK7TLR2TLR1ALDH1A1TSHR | |
| SCHEMBL10521155 | 0.78 | KLK7 (0.46) | KLK7TLR2TLR1 | |
| SCHEMBL1738812 | 0.77 | MDM2 (0.52) | KLK7TLR2TLR1 | |
| SCHEMBL6163528 | 0.77 | KLK7 (0.56) | KLK7TLR2TLR1ALDH1A1TSHR | |
| SCHEMBL7257138 | 0.76 | MAPT (0.45) | KLK7TLR2TLR1ALDH1A1TSHR | |
| SCHEMBL5169290 | 0.74 | ALDH1A1 (0.43) | KLK7ALDH1A1TSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4820691-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0296581-A2 | Amino acid 1,2-diketo derivatives as renin inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1988-12-28 | — | — | EP | disclosed |