Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | GRK3 | P35626 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441463 | 0.81 | MIF (0.40) | MIFALDH1A1NPC1HTTRAB9A | |
| SCHEMBL7402544 | 0.79 | ITGB3 (0.46) | ALDH1A1SMN1; SMN2ITGB3ITGA2BITGAV | |
| SCHEMBL7439572 | 0.79 | HRH4 (0.39) | ALDH1A1ITGB3ITGA2BITGAV | |
| SCHEMBL7442820 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7442838 | 0.76 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL7441446 | 0.74 | ITGB3 (0.46) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL7398371 | 0.74 | ITGB3 (0.48) | ITGB3ITGA2BITGAVCTSLCTSB | |
| SCHEMBL7402539 | 0.73 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL7398374 | 0.73 | ITGB3 (0.46) | ALDH1A1SMN1; SMN2ITGB3ITGA2BITGAV | |
| SCHEMBL7397826 | 0.72 | GLA (0.38) | ITGB3ITGA2BITGAVKMT2ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |