Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | GRK3 | P35626 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441471 | 0.81 | MIF (0.40) | MIFKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7439587 | 0.76 | BRD4 (0.39) | ITGB3ITGA2BBRD4 | |
| SCHEMBL7401123 | 0.72 | MIF (0.46) | MIFKMT2AMAPTMEN1KDM4E | |
| SCHEMBL7398372 | 0.70 | ITGB3 (0.40) | ITGB3ITGA2BBRD4 | |
| SCHEMBL7396918 | 0.67 | ITGB3 (0.68) | MIFITGB3ITGA2B | |
| SCHEMBL7433070 | 0.67 | ITGB3 (0.68) | MIFITGB3ITGA2B | |
| SCHEMBL7400579 | 0.66 | ITGB3 (0.43) | MIFKMT2AMAPTMEN1KDM4E | |
| SCHEMBL7400582 | 0.66 | ITGB3 (0.43) | MIFKMT2AMAPTMEN1KDM4E | |
| SCHEMBL6949755 | 0.65 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL7445076 | 0.65 | ITGB3 (0.56) | MIFITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674623-A1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014776-A2 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-07 | — | — | WO | disclosed |