Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487759 | 1.00 | RAB9A (0.36) | RAB9AKMT2ASLC6A4SIGMAR1L3MBTL1 | |
| SCHEMBL7489629 | 0.87 | SLC6A4 (0.38) | RAB9AKMT2ASLC6A4MEN1ROCK2 | |
| SCHEMBL7489622 | 0.87 | SLC6A4 (0.38) | RAB9AKMT2ASLC6A4MEN1ROCK2 | |
| SCHEMBL7488345 | 0.86 | F2 (0.36) | RAB9AKMT2ASIGMAR1L3MBTL1ALDH1A1 | |
| SCHEMBL7447108 | 0.86 | MEN1 (0.39) | RAB9AKMT2ASLC6A4MEN1ROCK2 | |
| SCHEMBL7496052 | 0.86 | MEN1 (0.39) | RAB9AKMT2ASLC6A4MEN1ROCK2 | |
| SCHEMBL7490466 | 0.82 | HRH3 (0.37) | SLC6A4ALDH1A1DPP4 | |
| SCHEMBL7490459 | 0.82 | HRH3 (0.37) | SLC6A4ALDH1A1DPP4 | |
| SCHEMBL7452435 | 0.81 | SLC6A4 (0.38) | KMT2ASLC6A4ALDH1A1 | |
| SCHEMBL7485841 | 0.81 | SLC6A4 (0.38) | KMT2ASLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918768-B1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RES LAB (KR) | 2002-01-09 | — | — | EP | disclosed |
| US-6201006-B1 | ANTICOAGULANTS | C & C RESEARCH LABORATORIES (KR) | 2001-03-13 | — | — | US | disclosed |
| EP-0918768-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C Research Laboratories (KR) | 1999-06-02 | — | — | EP | disclosed |
| WO-1997045424-A1 | AROMATIC AMIDINE DERIVATIVES USEFUL AS SELECTIVE THROMBIN INHIBITORS | C & C RESEARCH LABORATORIES (KR) | 1997-12-04 | — | — | WO | disclosed |