Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | OXTR | P30559 | 4/20 | 0.67 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366371 | 0.92 | OXTR (0.72) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL806651 | 0.91 | OXTR (0.66) | MAPTOXTRAVPR1AKMT2ASMN1; SMN2 | |
| SCHEMBL10053474 | 0.85 | MAPT (0.69) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL798403 | 0.85 | OXTR (0.69) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL5643910 | 0.80 | OXTR (1.00) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL16557537 | 0.80 | OXTR (0.77) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL744176 | 0.80 | OXTR (1.00) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL806760 | 0.79 | SMN1; SMN2 (0.75) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL806656 | 0.79 | MAPT (0.74) | MAPTTP53OXTRAVPR1AKMT2A | |
| SCHEMBL1630949 | 0.77 | KEAP1 (0.87) | MAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212134-B2 | Inhibitors of viral entry into mammalian cells | MICROBIOTIX, INC. (US) | 2015-12-15 | — | — | US | disclosed |