Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394046 | 0.89 | — | — | |
| SCHEMBL7381137 | 0.75 | NOS2 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL7412405 | 0.74 | NOS2 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL7597684 | 0.74 | NOS2 (0.35) | NOS3NOS1NOS2 | |
| SCHEMBL7412424 | 0.70 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL9013639 | 0.63 | HTR2A (0.52) | — | |
| SCHEMBL7420414 | 0.59 | CYP1A2 (0.56) | NOS3NOS1NOS2 | |
| SCHEMBL7417108 | 0.59 | BACE1 (0.51) | NOS3NOS2 | |
| SCHEMBL7380418 | 0.58 | CYP1A2 (0.36) | NOS3NOS1NOS2 | |
| SCHEMBL7420397 | 0.58 | NOS2 (0.49) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000073312-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-07 | — | — | WO | disclosed |