Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 17/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429887 | 0.93 | CRHR1 (0.56) | CRHR1 | |
| SCHEMBL7438143 | 0.90 | CRHR1 (0.42) | CRHR1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5600453 | 0.81 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL7441810 | 0.74 | CRHR1 (0.52) | CRHR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL5599676 | 0.74 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL5600448 | 0.72 | CRHR1 (0.86) | CRHR1 | |
| SCHEMBL5600230 | 0.71 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL5600460 | 0.71 | CRHR1 (0.52) | CRHR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL27670939 | 0.69 | CRHR1 (0.52) | CRHR1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL5599786 | 0.68 | CRHR1 (0.74) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149583-A2 | Combinations of corticotropin releasing factor antagonists and growth hormone secretagogues | Pfizer Products Inc. (US) | 2001-10-31 | — | — | EP | claimed |